Successful Management of Urosepsis with Ceftriaxone+Sulbactam+EDTA: A Case Report of Penem Sparing Approach
Published: September 1, 2017 | DOI: https://doi.org/10.7860/JCDR/2017/29146.10661
Amit Bery, Candy Sodhi, Rishu Bhanot
1. Consultant, Department of Internal Medicine, DMC, Ludhiana, Punjab, India.
2. Consultant, Department of Physiology, CMC, Ludhiana, Punjab, India.
3. Senior Resident, Department of Internal Medicine, DMC, Ludhiana, Punjab, India.
Correspondence
Dr. Amit Bery,
Consultant, Department of Internal Medicine, DMC, Ludhiana-141001, Punjab, India.
E-mail: amitbery@yahoo.co.in
Over the past decade, the Anti-Microbial Resistance (AMR) among members of Enterobacteriaceae family is on rise mainly due to rapid spread of strains producing Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo Beta-Lactamases (MBLs). Hence, the choice of drugs available for these resistant strains is diminishing and their treatment is becoming more challenging. This is a case of complicated Urinary Tract Infection (cUTI) due to ESBL producing E. coli leading to septic shock which was successfully managed with Antibiotic Adjuvant Entity (AAE), a combination of ceftriaxone+sulbactam+EDTA.
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